When most people heard that an ace pilot incurred so much brain damage that their ability to interface with a mech had been compromised, they would probably react with shock and dismay.
When Ves and Ketis heard the news that Isobel's brain may never be able to interface with a mech like the Promethea ever again, their reactions were remarkably muted.
An inability to use a neural interface to connect to a mech was no longer a crippling injury to them.
Didn't Benjamin Larkinson manage to regain the ability to pilot a mech despite the fact that he had to retire half a century earlier due to suffering permanent brain damage?
Since an old geezer who was previously a single step away from death managed to regain the ability to pilot a mech, then there was a chance for Saint Isobel to make a comeback as well!
The existence of the Carmine System was technically supposed to be a secret from most Larkinsons, but they weren't stupid. It was hard to suppress the spread of rumors.