Even by today's standards, the research on "Project C" was quite remarkable.
And the success of Project C also spurred another project to maturity—the Small Rejuvenation Pill project.
From two hundred years ago to today, the Restoring Enzyme's structure has been constantly fine-tuned, but its activation process and synthetic route have basically followed the original results.
As simple and reliable as the Restoring Enzyme is, so too is Project C safe and economical.
Up to today, Heroes and Protectors still use the Restoring Enzyme to reshape their brain neural networks and enhance their Internal Strength Cultivation.
Simply put, Yawgmoth did not just use "signal factors", he chose to insert a new protein.
This protein can be recognized by specific cell membrane receptors and enter the cell.